Electrospinning of PCL/CEFUROXIM® fibrous scaffolds on 3D printed collectors

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F20%3A00573189" target="_blank" >RIV/67985858:_____/20:00573189 - isvavai.cz</a>

Result on the web

<a href="https://hdl.handle.net/11104/0343646" target="_blank" >https://hdl.handle.net/11104/0343646</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1080/00405000.2019.1707347" target="_blank" >10.1080/00405000.2019.1707347</a>

Result language

angličtina

Original language name

Electrospinning of PCL/CEFUROXIM® fibrous scaffolds on 3D printed collectors

Original language description

In this paper, the effect of different collector geometry on the PCL scaffold architecture and cell viability was investigated. PCL scaffolds with antibiotic CefuroximVR, 15%wt. and 20%wt., were electrospun and characterized by ATR-FTIR, while thermal stability were observed by DSC and TG. PCL/15%CFUVR scaffolds were electrospun on six 3D printed collectors, three ribbed and three mesh geometries, to produce the most favourable structure for cells adhesion and proliferation. SEM study and MTT assay revealed that collectors with the widest slot in both ribbed and mesh geometries exhibited the most favourable structure to enhance cells adhesion. In general, cells spreading on the surface and cells via bility proved to be better for the ribbed collectors. The study showed that by controlling the collector geometry and the scaffold three-dimensional structure, it is possible to control cell attachment and differentiation and, consequently, to adjust them for the special tissue demands in the regeneration process.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30304 - Public and environmental health

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of the Textile Institute

ISSN

0040-5000

e-ISSN

1754-2340

Volume of the periodical

111

Issue of the periodical within the volume

9

Country of publishing house

GB - UNITED KINGDOM

Number of pages

12

Pages from-to

1288-1299

UT code for WoS article

000506136600001

EID of the result in the Scopus database

2-s2.0-85078636496