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INFLUENCE OF RESPIRATORY TRACT CONDITIONS ON PARTICLE SIZE DISTRIBUTIONS GENERATED BY COMMERCIALLY AVAILABLE INHALERS

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F23%3A00579895" target="_blank" >RIV/67985858:_____/23:00579895 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    INFLUENCE OF RESPIRATORY TRACT CONDITIONS ON PARTICLE SIZE DISTRIBUTIONS GENERATED BY COMMERCIALLY AVAILABLE INHALERS

  • Original language description

    Pressurized metered dose inhalers (MDI) and dry powder inhalers (DPI) are an integral part of the treatment of lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) (Vichrow et al., 2008). An important characteristic of particles dosed by MDI and DPI is particle size distribution (PSD) (Byron, 1990). This may vary depending on the formulation, but also on the temperature and relative humidity (RH) changes during the transport from the inhaler to the human respiratory tract. The aim of this study was to determine the influence of RH and inspiratory flow rates on the PSDncharacteristics and predict deposition efficiency of inhalable particles in the lungs.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10511 - Environmental sciences (social aspects to be 5.7)

Result continuities

  • Project

    <a href="/en/project/LTC17010" target="_blank" >LTC17010: Study on delivery efficiency of drugs dosed by aerosol inhalers to the target location in the respiratory tract</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    SBORNÍK XXII. VÝROČNÍ KONFERENCE ČESKÉ AEROSOLOVÉ SPOLEČNOSTI

  • ISBN

    978-80-908653-1-0

  • ISSN

  • e-ISSN

  • Number of pages

    2

  • Pages from-to

    61-62

  • Publisher name

    Česká aerosolová společnost, z.s

  • Place of publication

    Praha

  • Event location

    Čeladná

  • Event date

    Nov 13, 2023

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article