INFLUENCE OF RESPIRATORY TRACT CONDITIONS ON PARTICLE SIZE DISTRIBUTIONS GENERATED BY COMMERCIALLY AVAILABLE INHALERS
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985858%3A_____%2F23%3A00579895" target="_blank" >RIV/67985858:_____/23:00579895 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
INFLUENCE OF RESPIRATORY TRACT CONDITIONS ON PARTICLE SIZE DISTRIBUTIONS GENERATED BY COMMERCIALLY AVAILABLE INHALERS
Original language description
Pressurized metered dose inhalers (MDI) and dry powder inhalers (DPI) are an integral part of the treatment of lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) (Vichrow et al., 2008). An important characteristic of particles dosed by MDI and DPI is particle size distribution (PSD) (Byron, 1990). This may vary depending on the formulation, but also on the temperature and relative humidity (RH) changes during the transport from the inhaler to the human respiratory tract. The aim of this study was to determine the influence of RH and inspiratory flow rates on the PSDncharacteristics and predict deposition efficiency of inhalable particles in the lungs.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10511 - Environmental sciences (social aspects to be 5.7)
Result continuities
Project
<a href="/en/project/LTC17010" target="_blank" >LTC17010: Study on delivery efficiency of drugs dosed by aerosol inhalers to the target location in the respiratory tract</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
SBORNÍK XXII. VÝROČNÍ KONFERENCE ČESKÉ AEROSOLOVÉ SPOLEČNOSTI
ISBN
978-80-908653-1-0
ISSN
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e-ISSN
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Number of pages
2
Pages from-to
61-62
Publisher name
Česká aerosolová společnost, z.s
Place of publication
Praha
Event location
Čeladná
Event date
Nov 13, 2023
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
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