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Portable surface plasmon resonance biosensor for detection of nucleic acids

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F11%3A00437420" target="_blank" >RIV/67985882:_____/11:00437420 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.proeng.2011.12.037" target="_blank" >http://dx.doi.org/10.1016/j.proeng.2011.12.037</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.proeng.2011.12.037" target="_blank" >10.1016/j.proeng.2011.12.037</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Portable surface plasmon resonance biosensor for detection of nucleic acids

  • Original language description

    We present a portable surface plasmon resonance (SPR) sensor based on spectroscopy of surface plasmons on a special diffractive structure. The sensor combines a microfluidic cartridge incorporating the special diffractive structure functionalized with DNA probes and a compact SPR reader. We apply the sensor to detection of nucleic acids employing two most common immobilization methods: (a) biotinylated probes immobilized using the biotin-streptavidin chemistry and (b) thiolated probes attached directlyto the surface of the SPR sensor. It is demonstrated that both these immobilization methods allow detecting short nucleic acids at levels below 100 pM

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    JA - Electronics and optoelectronics

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Procedia Engineering

  • ISBN

    978-1-62748-581-4

  • ISSN

    1877-7058

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    148-151

  • Publisher name

    Elsevier

  • Place of publication

    Amsterdam

  • Event location

    Athens

  • Event date

    Sep 4, 2011

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article

    000300512400035