In vivo testing of a bioresorbable phosphate-based optical fiber

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F19%3A00518249" target="_blank" >RIV/67985882:_____/19:00518249 - isvavai.cz</a>

Alternative codes found

RIV/00179906:_____/19:10400308 RIV/60461373:22310/19:43919747

Result on the web

<a href="https://onlinelibrary.wiley.com/doi/full/10.1002/jbio.201800397" target="_blank" >https://onlinelibrary.wiley.com/doi/full/10.1002/jbio.201800397</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/jbio.201800397" target="_blank" >10.1002/jbio.201800397</a>

Result language

angličtina

Original language name

In vivo testing of a bioresorbable phosphate-based optical fiber

Original language description

Optical fibers have recently attracted a noticeable interest for biomedical applications because they provide a minimally invasive method for in vivo sensing, imaging techniques, deep-tissue photodynamic therapy or optogenetics. The silica optical fibers are the most commonly used because they offer excellent optical properties, and they are readily available at a reasonable price. The fused silica is a biocompatible material, but it is not bioresorbable so it does not decompose in the body and the fibers must be ex-planted after in vivo use and their fragments can present a considerable risk to the patient when the fiber breaks. In contrast, optical fibers made of phosphate glasses can bring many benefits because such glasses exhibit good transparency in ultraviolet-visible and near-infrared regions, and their solubility in water can be tailored by changing the chemical composition. The bioresorbability and toxicity of phosphate glass-based optical fibers were tested in vivo on male laboratory rats for the first time. The fiber was spliced together with a standard graded-index multi-mode fiber pigtail and an optical probe for in vitro pH measurement was prepared by the immobilization of a fluorescent dye on the fiber tip by a sol-gel method to demonstrate applicability and compatibility of the fiber with common fiber optics

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10306 - Optics (including laser optics and quantum optics)

Project

<a href="/en/project/NV15-33459A" target="_blank" >NV15-33459A: Biomedical photonic devices for advanced medicinal diagnostics and therapy</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Biophotonics

ISSN

1864-063X

e-ISSN

—

Volume of the periodical

12

Issue of the periodical within the volume

7

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

e201800397

UT code for WoS article

000477683300010

EID of the result in the Scopus database

2-s2.0-85063689976