Fast photothermal spatial light modulation for quantitative phase imaging at the nanoscale

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985882%3A_____%2F21%3A00551737" target="_blank" >RIV/67985882:_____/21:00551737 - isvavai.cz</a>
Alternative codes found
RIV/86652036:_____/21:00551737
Result on the web
<a href="https://doi.org/10.1038/s41467-021-23252-3" target="_blank" >https://doi.org/10.1038/s41467-021-23252-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1038/s41467-021-23252-3" target="_blank" >10.1038/s41467-021-23252-3</a>

Result language
angličtina
Original language name
Fast photothermal spatial light modulation for quantitative phase imaging at the nanoscale
Original language description
Spatial light modulators have become an essential tool for advanced microscopy, enabling breakthroughs in 3D, phase, and super-resolution imaging. However, continuous spatial-light modulation that is capable of capturing sub-millisecond microscopic motion without diffraction artifacts and polarization dependence is challenging. Here we present a photothermal spatial light modulator (PT-SLM) enabling fast phase imaging for nanoscopic 3D reconstruction. The PT-SLM can generate a step-like wavefront change, free of diffraction artifacts, with a high transmittance and a modulation efficiency independent of light polarization. We achieve a phase-shift > π and a response time as short as 70 µs with a theoretical limit in the sub microsecond range. We used the PT-SLM to perform quantitative phase imaging of sub-diffractional species to decipher the 3D nanoscopic displacement of microtubules and study the trajectory of a diffusive microtubule-associated protein, providing insights into the mechanism of protein navigation through a complex microtubule network
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10306 - Optics (including laser optics and quantum optics)

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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