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A COMPARISON OF THE CENTRIFUGAL FORCE SPINNING AND ELECTROSPINNING OF COLLAGEN UNDER DIFFERENT CONDITIONS

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985891%3A_____%2F17%3A00507423" target="_blank" >RIV/67985891:_____/17:00507423 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A COMPARISON OF THE CENTRIFUGAL FORCE SPINNING AND ELECTROSPINNING OF COLLAGEN UNDER DIFFERENT CONDITIONS

  • Original language description

    Collagen makes up one of the most important parts of the extracellular matrix and connective tissue. Collagen type I accounts for up to 90% of the collagen found in the body and it can be isolated and purified in large quantities and processed into a variety of forms. With respect to the process of the treatment of collagen into the nano-fibrous and submicron-fibrous forms, severe conditions leading to the denaturation of the collagen and thus the gelatin content should be avoided. Centrifugal force spinning and electrospinning processes appear to present promising methods for the spinning of collagen solutions. This paper deals with a comparison of the various methods applied in the processing of collagen, i.e. principally needle and needleless centrifugal spinning technology and electrospinning technology. In addition, the effect of process parameters and collagen solution conditions on the final form of the material was analyzed. Spun layers were prepared based on collagen type I isolated from calf skin. Nano-structured layers were prepared employing the spinning of 4-16 wt% collagen solutions in phosphate buffer saline and ethanol. The layers thus prepared were characterized by means of scanning electron microscopy and Fourier transform infrared spectroscopy.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    30404 - Biomaterials (as related to medical implants, devices, sensors)

Result continuities

  • Project

    <a href="/en/project/TA04010330" target="_blank" >TA04010330: Development of resorbable collagen-calcium phosphate nanolayer with controlled elution of antibiotics for implants survival rate enhancement</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2017

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    8th International Conference on Nanomaterials - Research and Application (NANOCON 2016)

  • ISBN

    978-80-87294-71-0

  • ISSN

  • e-ISSN

  • Number of pages

    6

  • Pages from-to

    514-519

  • Publisher name

    TANGER

  • Place of publication

    Ostrava

  • Event location

    Brno

  • Event date

    Oct 19, 2016

  • Type of event by nationality

    EUR - Evropská akce

  • UT code for WoS article

    000410656100090