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Allelic variation in porcine resistin (RETN) gene is associated with fatness traits in a Wild Boar x Meishan reference family

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F06%3A00054487" target="_blank" >RIV/67985904:_____/06:00054487 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Allelic variation in porcine resistin (RETN) gene is associated with fatness traits in a Wild Boar x Meishan reference family

  • Original language description

    Cloning and comparative sequencing of the porcine resistin (RETN) gene and 5? flanking region, located at 64 cM on SSC2, revealed 9 SNPs and 2 indels. A European Wild Boar x Meishan family encompassing 335 F2 animals measured for 46 traits including growth, fat deposition and muscle accretion was scored for a T2094C polymorphism by means of MvaI PCR-RFLP. Two haplotypes (AM157180 and AM157181) segregated in the family while the imprinted QTL in IGF2 was fixed. The founder boar was homozygote MvaI BB while Meishan F0 sows segregated alleles MvaI A and MvaI B. Previous QTL mapping by Lee et al. (2003) did not reveal any QTL for fat accretion in the MYOD - SW395 interval where RETN is located. Association analysis showed that the MvaI A allele of Meishanorigin accompanied by the 1472A allele encoding for 36Ala is associated with higher values for fat deposition traits (fat depth at 10th rib, back fat depth at 13th/14th rib, loin fat depth, average back fat depth, back fat weight, ham sub

  • Czech name

    Alelická variabilita prasečího resistinového (RETN ) genu je asociována s ukládáním tuku u referenční rodiny divoké prase x meishan

  • Czech description

    Klonováním a komparativním sekvenováním prasečího resistinového genu, lokalizovaného na v pozici 64 na SSC2, cM a 5? přiléhající oblasti bylo zjištěno 9 SNP a indely. Rodina divoké prase x meishan mající 335 F2 potomků, u kterých bylo zjišťováno 46 vlastností (včetně růstu, ukládání tuku a růstu svalů) a byli pomocí MvaI PCR-RFLP testováni na polymorfismus T2094C . V rodine segregovaly dva haplotypy (AM157180 a AM157181)zatím co imprintovaný QTL v IGF2 byl fixován.

Classification

  • Type

    D - Article in proceedings

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA523%2F04%2F0106" target="_blank" >GA523/04/0106: A molecular genetic study of porcine variability for fat deposition</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2006

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    Proceedings of the 30th International Conference on Animal Genetics ISAG 2006

  • ISBN

    85-85584-02-5

  • ISSN

  • e-ISSN

  • Number of pages

    1

  • Pages from-to

    72

  • Publisher name

    ISAG

  • Place of publication

    Porto Seguro

  • Event location

    Porto Seguro

  • Event date

    Aug 20, 2006

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article