AllergoOncology - the impact of allergy in oncology: EAACI position paper

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00475947" target="_blank" >RIV/67985904:_____/17:00475947 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1111/all.13119" target="_blank" >http://dx.doi.org/10.1111/all.13119</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1111/all.13119" target="_blank" >10.1111/all.13119</a>

Result language

angličtina

Original language name

AllergoOncology - the impact of allergy in oncology: EAACI position paper

Original language description

Th2 immunity and allergic immune surveillance play critical roles in host responses to pathogens, parasites and allergens. Numerous studies have reported significant links between Th2 responses and cancer, including insights into the functions of IgE antibodies and associated effector cells in both antitumour immune surveillance and therapy. The interdisciplinary field of AllergoOncology was given Task Force status by the European Academy of Allergy and Clinical Immunology in 2014. Affiliated expert groups focus on the interface between allergic responses and cancer, applied to immune surveillance, immunomodulation and the functions of IgE-mediated immune responses against cancer, to derive novel insights into more effective treatments. Coincident with rapid expansion in clinical application of cancer immunotherapies, here we review the current state-of-the-art and future translational opportunities, as well as challenges in this relatively new field. Recent developments include improved understanding of Th2 antibodies, intratumoral innate allergy effector cells and mediators, IgE-mediated tumour antigen cross-presentation by dendritic cells, as well as immunotherapeutic strategies such as vaccines and recombinant antibodies, and finally, the management of allergy in daily clinical oncology. Shedding light on the crosstalk between allergic response and cancer is paving the way for new avenues of treatment.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30225 - Allergy

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2017

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Allergy

ISSN

0105-4538

e-ISSN

—

Volume of the periodical

72

Issue of the periodical within the volume

6

Country of publishing house

DK - DENMARK

Number of pages

22

Pages from-to

866-887

UT code for WoS article

000402834300005

EID of the result in the Scopus database

2-s2.0-85010387157