Potential Involment of SCF - Complex in Zygotic Genome Activation During Early Bovine Embryo Development

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F17%3A00488245" target="_blank" >RIV/67985904:_____/17:00488245 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-1-4939-6988-3" target="_blank" >http://dx.doi.org/10.1007/978-1-4939-6988-3</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-1-4939-6988-3" target="_blank" >10.1007/978-1-4939-6988-3</a>

Result language
angličtina
Original language name
Potential Involment of SCF - Complex in Zygotic Genome Activation During Early Bovine Embryo Development
Original language description
Proper timing of degradation of maternal protein reserves is important for early embryonic development. The major modification that triggers proteins to degradation is ubiquitination, mediated by ubiquitin-proteolytic system. We focus here on Skp 1-Cul 1-F-box complex (SCF-complex), E3 ubiquitin-ligase, a part of ubiquitin-proteolytic system, which transfer ubiquitin to the substrate protein. We describe in this chapter the methods for the characterization of the expression profile of mRNA and protein of invariant members of SCF-complex and for the definition of SCF-complex activity.
Czech name
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Czech description
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Project
<a href="/en/project/GP13-24730P" target="_blank" >GP13-24730P: The Role of Skp1-Cullin1-F-box Complex in Protein Ubiquitination and Degradation during Bovine Preimplantation Development</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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