Periderm invasion contributes to epithelial formation in the teleost pharynx

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F19%3A00517157" target="_blank" >RIV/67985904:_____/19:00517157 - isvavai.cz</a>

Result on the web

<a href="https://www.nature.com/articles/s41598-019-46040-y" target="_blank" >https://www.nature.com/articles/s41598-019-46040-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-019-46040-y" target="_blank" >10.1038/s41598-019-46040-y</a>

Result language

angličtina

Original language name

Periderm invasion contributes to epithelial formation in the teleost pharynx

Original language description

The gnathostome pharyngeal cavity functions in food transport and respiration. In amniotes the mouth and nares are the only channels allowing direct contact between internal and external epithelia. In teleost fish, gill slits arise through opening of endodermal pouches and connect the pharynx to the exterior. Using transgenic zebrafish lines, cell tracing, live imaging and different markers, we investigated if pharyngeal openings enable epithelial invasion and how this modifies the pharyngeal epithelium. We conclude that in zebrafish the pharyngeal endoderm becomes overlain by cells with a peridermal phenotype. In a wave starting from pouch 2, peridermal cells from the outer skin layer invade the successive pouches until halfway their depth. Here the peridermal cells connect to a population of cells inside the pharyngeal cavity that express periderm markers, yet do not invade from outside. The latter population expands along the midline from anterior to posterior until the esophagusgut boundary. Together, our results show a novel role for the periderm as an internal epithelium becomes adapted to function as an external surface.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10605 - Developmental biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Cells

ISSN

2073-4409

e-ISSN

—

Volume of the periodical

9

Issue of the periodical within the volume

JUL 12

Country of publishing house

CH - SWITZERLAND

Number of pages

13

Pages from-to

10082

UT code for WoS article

000475292700004

EID of the result in the Scopus database

2-s2.0-85068970089