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Gene therapy of monogenic diseases

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F20%3A00536561" target="_blank" >RIV/67985904:_____/20:00536561 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Gene therapy of monogenic diseases

  • Original language description

    Gene therapy repairs or modifies the expression of individual gene in targeted cells by transfer of nucleic material to the cells. The development of the gene therapy has been impressive over the last decade. It can reduce the production of mutated proteins causing the disease, elevate the production of proteins curing the disease, or produce modified or new proteins. Here we briefly review the main alternatives of gene targeting together with the options of delivery to the cells.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    10603 - Genetics and heredity (medical genetics to be 3)

Result continuities

  • Project

    <a href="/en/project/LO1609" target="_blank" >LO1609: Models of the Serious Human Diseases: Traumatic Spinal Cord Injury, Huntington’s Disease, Melanoma and Infertility</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Translational Research in Serious Human Diseases

  • ISBN

    978-80-200-3158-7

  • Number of pages of the result

    6

  • Pages from-to

    148-153

  • Number of pages of the book

    271

  • Publisher name

    Academia

  • Place of publication

    Praha

  • UT code for WoS chapter