EFFECT OF DIETARY SUPPLEMENTATION WITH DRIED TUBER OF JERUSALEM ARTICHOKE ON SKATOLE LEVEL IN BACKFAT AND CYP2E1 mRNA EXPRESSION IN LIVER OF BOARS

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F21%3A00550739" target="_blank" >RIV/67985904:_____/21:00550739 - isvavai.cz</a>

Alternative codes found

RIV/60460709:41210/21:88314

Result on the web

<a href="https://www.sciendo.com/article/10.2478/aoas-2020-0119" target="_blank" >https://www.sciendo.com/article/10.2478/aoas-2020-0119</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.2478/aoas-2020-0119" target="_blank" >10.2478/aoas-2020-0119</a>

Result language

angličtina

Original language name

EFFECT OF DIETARY SUPPLEMENTATION WITH DRIED TUBER OF JERUSALEM ARTICHOKE ON SKATOLE LEVEL IN BACKFAT AND CYP2E1 mRNA EXPRESSION IN LIVER OF BOARS

Original language description

The objective of this study was to investigate the effect of diets containing different levels of dried tuber of Jerusalem artichoke, Helianthus tuberosus, on skatole levels in backfat and on the CYP2E1 mRNA expression in the liver of commercial crossbred pigs. A total of 23 uncastrated male pigs from 10 litters of a commercial crossbred population of Large White x (Landrace x Large White), were used in this study. Boars were randomly divided into four different dietary treatment groups - a control group (K1, 5 boars, without supplementation of Jerusalem artichoke) and three experimental groups (6 boars each) that were fed with the diet containing different levels of dried Jerusalem artichoke (K2 - 4.1%, K3 - 8.2%, K4 - 12.2%) for 14 days before slaughter. Significant effects of diet on skatole levels were observed between the control group and the experimental groups (P = 0.0078). The lowest level of skatole was in the K3 group with 8.2% of Jerusalem artichoke. As for CYP2E1, a negative correlation was observed between the levels of skatole and CYP2E1 mRNA expression. Significant effect (P = 0.0055) was found in all experimental groups compared to the K1 group, and most pronounced in the K2 and K3 groups. The supplementation with Jerusalem artichoke resulted in lower level of skatole and higher CYP2E1 mRNA expression. The results suggest that affecting the expression of CYP2E1 by feed supplements could be an option to effectively reduce the levels of skatole in adipose tissue of entire male pigs.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

40201 - Animal and dairy science; (Animal biotechnology to be 4.4)

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Annals of Animal Science

ISSN

1642-3402

e-ISSN

2300-8733

Volume of the periodical

21

Issue of the periodical within the volume

4

Country of publishing house

PL - POLAND

Number of pages

15

Pages from-to

1475-1489

UT code for WoS article

000729942700017

EID of the result in the Scopus database

2-s2.0-85105608949