Possible effects of the MC4R Asp298Asn polymorphism on pig production traits under ad libitum versus restricted feeding
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985904%3A_____%2F23%3A00569355" target="_blank" >RIV/67985904:_____/23:00569355 - isvavai.cz</a>
Alternative codes found
RIV/60460709:41210/23:92301
Result on the web
<a href="https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=6473188838" target="_blank" >https://asep.lib.cas.cz/arl-cav/cs/csg/?repo=crepo1&key=6473188838</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/jbg.12751" target="_blank" >10.1111/jbg.12751</a>
Alternative languages
Result language
angličtina
Original language name
Possible effects of the MC4R Asp298Asn polymorphism on pig production traits under ad libitum versus restricted feeding
Original language description
The missense mutation Asp298Asn in the melanocortin 4 receptor (MC4R) is associated with daily gain or fatness in pigs (Sus scrofa domesticus). However, to the best of our knowledge, no study has directly compared the effects of the polymorphism between different feeding levels, even though diet plays a vital role in the swine industry. To explore possible differences, data from 439 mostly commercial hybrids fattened ad libitum and 119 commercial hybrids fattened with restricted feed ration were collected. The recorded traits were average daily gain (ADG), feed conversion ratio (FCR), carcass weight (CW), dressing percentage (DP), lean meat content (LM), backfat thickness (BFT), lean cuts weight, and meat quality parameters such as pH, temperature, drip loss, and CIELAB colour space. The general linear model revealed that the overall effect of MC4R was not statistically significant, but significant differences (p < 0.05) were found in ADG, FCR, CW, DP, LM, and BFT. In the ad libitum category, the AA genotype (298Asn/298Asn) tended to be the most favourable for growth-related traits, with the lowest LM, which is consistent with previous findings. In the restricted category, on the other hand, GA heterozygotes (298Asp/298Asn) achieved the best performance in terms of growth, whereas AA homozygotes showed the worst performance. Therefore, these results raise the possibility of an interaction between MC4R and the feeding level.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10603 - Genetics and heredity (medical genetics to be 3)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Animal Breeding and Genetics
ISSN
0931-2668
e-ISSN
1439-0388
Volume of the periodical
140
Issue of the periodical within the volume
2
Country of publishing house
DE - GERMANY
Number of pages
9
Pages from-to
207-215
UT code for WoS article
000905779800001
EID of the result in the Scopus database
2-s2.0-85145339821