A migration-driven model for the historical spread of leprosy in medieval Eastern and Central Europe
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985912%3A_____%2F15%3A00448989" target="_blank" >RIV/67985912:_____/15:00448989 - isvavai.cz</a>
Alternative codes found
RIV/00023272:_____/15:#0002752
Result on the web
<a href="http://dx.doi.org/10.1016/j.meegid.2015.02.001" target="_blank" >http://dx.doi.org/10.1016/j.meegid.2015.02.001</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.meegid.2015.02.001" target="_blank" >10.1016/j.meegid.2015.02.001</a>
Alternative languages
Result language
angličtina
Original language name
A migration-driven model for the historical spread of leprosy in medieval Eastern and Central Europe
Original language description
Leprosy was rare in Europe during the Roman period, yet its prevalence increased dramatically in medieval times. We examined human remains, with paleopathological lesions indicative of leprosy, dated to the 6th-11th century AD, from Central and Eastern Europe and Byzantine Anatolia. Analysis of ancient DNA and bacterial cell wall lipid biomarkers revealed Mycobacterium leprae in skeletal remains from 6th-8th century Northern Italy, 7th-11th century Hungary, 8th-9th century Austria, the Slavic Greater Moravian Empire of the 9th-10th century and 8th-10th century Byzantine samples from Northern Anatolia. These data were analyzed alongside findings published by others. M. leprae is an obligate human pathogen that has undergone an evolutionary bottleneck followed by clonal expansion. Therefore M. leprae genotypes and sub-genotypes give information about the human populations they have infected and their migration. Although data are limited, genotyping demonstrates that historical M. leprae
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
AC - Archaeology, anthropology, ethnology
OECD FORD branch
—
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Infection, Genetics and Evolution
ISSN
1567-1348
e-ISSN
—
Volume of the periodical
31
Issue of the periodical within the volume
April
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
7
Pages from-to
250-256
UT code for WoS article
000352182900034
EID of the result in the Scopus database
2-s2.0-84923030250