Population history and genetic adaptation of the Fulani nomads: inferences from genome-wide data and the lactase persistence trait
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985912%3A_____%2F19%3A00517502" target="_blank" >RIV/67985912:_____/19:00517502 - isvavai.cz</a>
Result on the web
<a href="https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/s12864-019-6296-7" target="_blank" >https://bmcgenomics.biomedcentral.com/track/pdf/10.1186/s12864-019-6296-7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1186/s12864-019-6296-7" target="_blank" >10.1186/s12864-019-6296-7</a>
Alternative languages
Result language
angličtina
Original language name
Population history and genetic adaptation of the Fulani nomads: inferences from genome-wide data and the lactase persistence trait
Original language description
Through several genomic analyses we show that the present-day Fulani diversity is the result of an admixture between a West African group and a group/s that carried European and North African ancestry. The European variant associated with lactase persistence (capacity to digest lactose in adulthood) was likely introduced through this admixture event, and was strongly selected in successive generations. We show also that the region with the lactase gene was not the only one that was under strong selective pressure in the ancestral population leading to the contemporary Fulani pastoralists as several other selection signals were detected in our dataset. It can be suggested that these genetic advantages contributed to population expansion of the pastoralists and long range spread across the Sahel/Savannah belt of Africa.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
60102 - Archaeology
Result continuities
Project
<a href="/en/project/GA19-09352S" target="_blank" >GA19-09352S: Genomic Adaptations and Molecular Ecology of Food Production Systems</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
BMC Genomics
ISSN
1471-2164
e-ISSN
—
Volume of the periodical
20
Issue of the periodical within the volume
1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
915
UT code for WoS article
000501323300001
EID of the result in the Scopus database
2-s2.0-85076088989