Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F67985939%3A_____%2F16%3A00471908" target="_blank" >RIV/67985939:_____/16:00471908 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/16:00093526
Result on the web
<a href="http://dx.doi.org/10.1093/toxsci/kfw114" target="_blank" >http://dx.doi.org/10.1093/toxsci/kfw114</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/toxsci/kfw114" target="_blank" >10.1093/toxsci/kfw114</a>

Result language
angličtina
Original language name
Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells
Original language description
Endocrine disruptors interfere with physiological hormonal regulations. We showed using mammalian cell cultures that endocrine disruptors methoxychlor and vinclozolin can elicit effects also independently of estrogen- or androgen-receptor. In this way, they can disrupt gap junctional intercellular communication or activity of signal transduction enzymes. These findings improve our understanding about mode of action of these important environmental contaminants and their human health impacts.
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
—

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)