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Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F08%3A00318537" target="_blank" >RIV/68081707:_____/08:00318537 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Epigenome and chromatin structure in human embryonic stem cells undergoing differentiation

  • Original language description

    Analyses showed that H3K9 trimethylation, variants of HP1 proteins and centromeric heterochromatin are important markers how to distinguish between pluripotent and differentiated stages of human embryonic stem cells (hESCs). Conversely, except centromeres, nuclear radial distributions were conserved in pluripotent and differentiated hESCs.

  • Czech name

    Epigenom a struktura chromatinu u lidských embryonálních kmenových buněk stimulovaných k diferenciaci

  • Czech description

    Analýzy ukázaly, že H3K9 trimethylace, varianty HP1 proteinu a centromerický heterochromatin jsou důležité markery pro rozlišení mezi pluripotentním a diferencovaným stavem lidských embryonálních kmenových buněk (hESCs). Na druhou stranu, kromě centromer, radiální distribuce chromatinu jsou z velké části shodné jak u pluripotentních, tak diferencovaných hES buněk.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Developmental Dynamics

  • ISSN

    1058-8388

  • e-ISSN

  • Volume of the periodical

    237

  • Issue of the periodical within the volume

    12

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    13

  • Pages from-to

  • UT code for WoS article

    000261679300022

  • EID of the result in the Scopus database