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Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F10%3A00351205" target="_blank" >RIV/68081707:_____/10:00351205 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216224:14310/10:00049637

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2

  • Original language description

    Dishevelled (Dvl) is a multifunctional effector of different Wnt cascades. We provide evidence that Dvl phosphorylated by casein kinase 1 epsilon can bind atypical receptor kinase Ror2. We show that CK1-phosphorylated Dvl induced by both canonical and non-canonical Wnt ligands triggers negative feedback regulation in a Ror2-dependent manner.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    BO - Biophysics

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    FASEB Journal

  • ISSN

    0892-6638

  • e-ISSN

  • Volume of the periodical

    24

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

  • UT code for WoS article

    000279343600028

  • EID of the result in the Scopus database