Hyaluronan minimizes effects of UV irradiation on human keratinocytes

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F11%3A00359410" target="_blank" >RIV/68081707:_____/11:00359410 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00403-011-1146-8" target="_blank" >http://dx.doi.org/10.1007/s00403-011-1146-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00403-011-1146-8" target="_blank" >10.1007/s00403-011-1146-8</a>

Result language
angličtina
Original language name
Hyaluronan minimizes effects of UV irradiation on human keratinocytes
Original language description
Exposure to ultraviolet (UV) irradiation has detrimental effects on skin accompanied by the increased metabolism of hyaluronan (HA). Immortalized human keratinocytes (HaCaT) were irradiated by a single dose of UVB and immediately treated with HA for 6 and 24 h. The expressions of HA synthase-3 and hyaluronidase-3 were not significantly odulated by UV irradiation. In contrast, HA significantly suppressed UVB-induced proinflammatory cytokine release including interleukin-6 and interleukin-8.
Czech name
—
Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BO - Biophysics
OECD FORD branch
—

Project
<a href="/en/project/GA305%2F08%2F1704" target="_blank" >GA305/08/1704: Role of hyaluronan of different molecular weight in the course of inflammation</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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