Label-free electrochemical analysis of purine nucleotides and nucleobases at disposable carbon electrodes in microliter volumes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F19%3A00518362" target="_blank" >RIV/68081707:_____/19:00518362 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S157266571930520X?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S157266571930520X?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.jelechem.2019.113252" target="_blank" >10.1016/j.jelechem.2019.113252</a>
Alternative languages
Result language
angličtina
Original language name
Label-free electrochemical analysis of purine nucleotides and nucleobases at disposable carbon electrodes in microliter volumes
Original language description
We analyzed purine nucleotides in oligodeoxynucleotides (ODN) and nucleobase residues acid-hydrolyzed ODN at nanomolar concentrations in few tens of microliters of solution at commercially available unmodified graphite pencil electrodes, screen printed graphite electrodes (SPGEs) and SPGEs modified by graphene, single- and multi-walled carbon nanotubes. Our results suggest that specific properties of different graphite-based electrodes have significant impact on ODN analysis. Nanostructure-modified electrodes produced higher signals due to purine nucleobase oxidation but also higher background currents. The unmodified disposable carbon electrodes allowed analysis of both free nucleobases and ODNs. Our results show that unmodified SPGEs represent a good compromise for signal/noise ratio. Electrooxidation of purines at these electrodes was only little affected by the presence of pyrimidines in contrast to the pencil graphite electrode.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Electroanalytical Chemistry
ISSN
1572-6657
e-ISSN
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Volume of the periodical
847
Issue of the periodical within the volume
AUG 15 2019
Country of publishing house
CH - SWITZERLAND
Number of pages
7
Pages from-to
113252
UT code for WoS article
000482532200065
EID of the result in the Scopus database
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