The rDNA Loci-Intersections of Replication, Transcription, and Repair Pathways
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F21%3A00542084" target="_blank" >RIV/68081707:_____/21:00542084 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14740/21:00121265
Result on the web
<a href="https://www.mdpi.com/1422-0067/22/3/1302" target="_blank" >https://www.mdpi.com/1422-0067/22/3/1302</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms22031302" target="_blank" >10.3390/ijms22031302</a>
Alternative languages
Result language
angličtina
Original language name
The rDNA Loci-Intersections of Replication, Transcription, and Repair Pathways
Original language description
Genes encoding ribosomal RNA (rDNA) are essential for cell survival and are particularly sensitive to factors leading to genomic instability. Their repetitive character makes them prone to inappropriate recombinational events arising from collision of transcriptional and replication machineries, resulting in unstable rDNA copy numbers. In this review, we summarize current knowledge on the structure and organization of rDNA, its role in sensing changes in the genome, and its linkage to aging. We also review recent findings on the main factors involved in chromatin assembly and DNA repair in the maintenance of rDNA stability in the model plants Arabidopsis thaliana and the moss Physcomitrella patens, providing a view across the plant evolutionary tree.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Molecular Sciences
ISSN
1422-0067
e-ISSN
1422-0067
Volume of the periodical
22
Issue of the periodical within the volume
3
Country of publishing house
CH - SWITZERLAND
Number of pages
14
Pages from-to
1302
UT code for WoS article
000615329800001
EID of the result in the Scopus database
2-s2.0-85099970895