Electrochemical analysis of proteins important in cancer: Behavior of anterior gradient receptors, p53 protein and their complexes at charged surfaces

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F23%3A00572133" target="_blank" >RIV/68081707:_____/23:00572133 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S2451910323000625?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S2451910323000625?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.coelec.2023.101269" target="_blank" >10.1016/j.coelec.2023.101269</a>

Result language
angličtina
Original language name
Electrochemical analysis of proteins important in cancer: Behavior of anterior gradient receptors, p53 protein and their complexes at charged surfaces
Original language description
Electrochemical methods are one of the most utilized approaches for newly developing strategies of cancer biomarker detection. However, electrochemical methods can be used in cancer research also as techniques applicable for fast preliminary tests of protein structural changes and for clarifying protein interactions with the interacting partners including DNA, proteins, and peptides. In this review, we present some examples of electrochemical approaches, which help to understand the role of cancer protein(s) in biological pathways. Data obtained with protein p53 and anterior gradient proteins using chronopotentiometric stripping analysis provide information about the structural dynamics of a given protein and its complexes. The knowledge about biomacromolecule behavior at the charged surfaces can be further utilized in other fields including molecular biology, proteomics, glycomics as well as in sensorics.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project
<a href="/en/project/GA22-26590S" target="_blank" >GA22-26590S: New tools for research and diagnostics of glycans and glycoproteins using electrochemical analysis and chemical modification.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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