Pickering emulsions as an effective route for the preparation of bioactive composites: A study of nanocellulose/polyaniline particles with immunomodulatory effect

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081707%3A_____%2F24%3A00600738" target="_blank" >RIV/68081707:_____/24:00600738 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28610/24:63575758 RIV/70883521:28110/24:63575758

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0144861723008949?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0144861723008949?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.carbpol.2023.121429" target="_blank" >10.1016/j.carbpol.2023.121429</a>

Result language

angličtina

Original language name

Pickering emulsions as an effective route for the preparation of bioactive composites: A study of nanocellulose/polyaniline particles with immunomodulatory effect

Original language description

Several studies have reported on application of cellulose particles for stabilizing Pickering emulsions (PE). Here we employ an original approach that involves using these particles as a part of advanced composite colloids made of conducting polymer polyaniline (PANI) and cellulose nanocrystals (CNC) or nanofibrils (CNF). PANI/cellulose particles were prepared using oxidative polymerization of aniline in situ in the presence of CNC or CNF. The type and amount of celluloses (CNC vs CNF) and concentration of precursors (aniline monomer and oxidant) used in the reaction determined properties of the colloidal particles, such as size, morphology and content of PANI. The particles demonstrated intriguing biological characteristics, including no cytotoxicity, antibacterial activity against Staphylococcus aureus and Escherichia coli, antioxidant activity and related immunomodulatory activity. For the first time, such composites were used to successfully stabilize oil-in-water PE with undecane or capric/ caprylic triglyceride oils. The properties of the emulsions were determined by the PANI/cellulose particles and oil used. The key finding of the study is the demonstrated ability of PANI/cellulose particles to stabilize PE, as well as the excellent antioxidant activity and ROS scavenging action originating from PANI presence, indicating potential of such systems for use in biomedicine, particularly for wound healing.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10404 - Polymer science

Project

<a href="/en/project/GA23-07425S" target="_blank" >GA23-07425S: Anisotropic and Electro-Conducting Biomaterials</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2024

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Carbohydrate Polymers

ISSN

0144-8617

e-ISSN

1879-1344

Volume of the periodical

323

Issue of the periodical within the volume

JAN 1 2024

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

14

Pages from-to

121429

UT code for WoS article

001097327100001

EID of the result in the Scopus database

2-s2.0-85172412582