Considerations on electrolysis in electromembrane extraction of basic drugs
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F15%3A00448871" target="_blank" >RIV/68081715:_____/15:00448871 - isvavai.cz</a>
Result on the web
<a href="http://www.ce-ce.org/CECE2015/CECE%202015%20proceedings_full.pdf" target="_blank" >http://www.ce-ce.org/CECE2015/CECE%202015%20proceedings_full.pdf</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Considerations on electrolysis in electromembrane extraction of basic drugs
Original language description
Electrolysis may significantly affect composition and pH values of non-optimized acceptor solutions and have fatal consequences on quantitative EME results for weak and medium strong analytes. Acceptor solutions consisting of high concentrations of weakacids have therefore been proposed as suitable operational solutions for electromembrane extraction (EME) of selected basic drugs. 500 mM formic acid efficiently eliminated the electrolytically produced OH? ions, offered constant pH and thus long-term EME performance and was easily compatible with subsequent analytical methods. Maximum EME recoveries ranged from 66 to 89% and were constant between 40 and 80 min of EME and no back-extraction of the analytes into donor solutions was observed.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA13-05762S" target="_blank" >GA13-05762S: Theory, methodology and development of progressive chemical methods for analysis of trace components and complex samples by capillary electrophoresis.</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
CECE 2015. 12th International Interdisciplinary Meeting on Bioanalysis
ISBN
978-80-904959-3-7
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
198-201
Publisher name
Ústav analytické chemie AV ČR, v. v. i
Place of publication
Brno
Event location
Brno
Event date
Sep 21, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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