Nanostructured gold deposited in gelatin template applied for electrochemical assay of glucose in serum

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F16%3A00464713" target="_blank" >RIV/68081715:_____/16:00464713 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14740/16:00089213

Result on the web

<a href="http://dx.doi.org/10.1016/j.electacta.2015.12.009" target="_blank" >http://dx.doi.org/10.1016/j.electacta.2015.12.009</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.electacta.2015.12.009" target="_blank" >10.1016/j.electacta.2015.12.009</a>

Result language

angličtina

Original language name

Nanostructured gold deposited in gelatin template applied for electrochemical assay of glucose in serum

Original language description

Gelatin-templated gold nanostructures were fabricated in order to improve the sensitivity of nonenzymatic determination of glucose. The three-dimensional cavities were created by crosslinking of gelatin layer on the electrode and the specific saw tooth-like morphology of surface was formed by electrodeposition of gold through the cavities. Scanning electron microscopy (SEM) and atomic force microscopy (AFM) were used for the investigation of nanostructure growth and characterization of prepared surfaces. Glucose was detected by a direct electrochemical oxidation during cyclic voltammetry in alkaline solution with excellent sensitivity of 1165 mA mM 1cm 2, wide linear range from 32 mM to 10 mM and limit of detection (LOD) of 90 mM. During amperometric measurements LOD of 1.5 mM was achieved. The sensor was able to detect real concentrations of glucose in deproteinized human serum with negligible interference of oxidizable blood components. Great correlation with results obtained from reference methods (commercial glucometer and standard kit for photometric glucose detection) was demonstrated; the determination of glucose in serum was performed with relative standard deviation of 4%. The sensor exhibits a strong potential as a rapid and sensitive non-enzymatic approach in future applications for clinical analyses.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CB - Analytical chemistry, separation

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Electrochimica acta

ISSN

0013-4686

e-ISSN

—

Volume of the periodical

188

Issue of the periodical within the volume

JAN

Country of publishing house

GB - UNITED KINGDOM

Number of pages

9

Pages from-to

277-285

UT code for WoS article

000370986500032

EID of the result in the Scopus database

2-s2.0-84949604623