Immobilization of a phosphonium ionic liquid on a silica monolith forhydrophilic interaction chromatography

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F18%3A00490130" target="_blank" >RIV/68081715:_____/18:00490130 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.chroma.2018.04.012" target="_blank" >http://dx.doi.org/10.1016/j.chroma.2018.04.012</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.chroma.2018.04.012" target="_blank" >10.1016/j.chroma.2018.04.012</a>

Result language
angličtina
Original language name
Immobilization of a phosphonium ionic liquid on a silica monolith forhydrophilic interaction chromatography
Original language description
A methodology for preparing phosphonium-based ionic liquid modified silica-based monolithic cap-illary columns is presented. The silica monolithic columns with dimensions of 150 × 0.1 mm weremodified by a phosphonium-based ionic liquid (trioctyl(3/4-vinylbenzyl)phosphonium chloride) via3-(trimethoxysilyl)propyl methacrylate. The prepared columns were evaluated under hydrophilic inter-action liquid chromatography separation conditions, employing a sample mixture containing purine andpyrimidine bases and nucleosides. Detection was made by UV. The high efficiency of the original silicamonolith was preserved even after modification, and it reached values in the range of 98,000–174,000theoretical plates/m. The effects of the concentration of acetonitrile in the mobile phase, the presence ofadditives in the mobile phase, such as, acetic acid or ammonium acetate, and the pH of the mobile phaseon the separation of some selected analytes were investigated. The prepared columns showed differentseparation selectivity compared to silica, phenyl and sulfobetaine stationary phases.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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