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Rapid fabrication of microextraction devices for direct determination of basic drugs in dried blood spots

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F18%3A00499020" target="_blank" >RIV/68081715:_____/18:00499020 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216305:26310/18:PU130346

  • Result on the web

    <a href="http://www.ce-ce.org/user_uploads/program/CECE%202018%20Proceedings_WOS.pdf" target="_blank" >http://www.ce-ce.org/user_uploads/program/CECE%202018%20Proceedings_WOS.pdf</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Rapid fabrication of microextraction devices for direct determination of basic drugs in dried blood spots

  • Original language description

    A 3D-printed cutter was designed for rapid fabrication of supported liquid membrane (SLM) extraction devices compatible with injection system of commercial capillary electrophoresis (CE) instrument. Low cost and single use microextraction devices were fabricated from polypropylene micropipette tips with high precision (dimension variances ≤ 3% RSD). Practical applicability of the microextraction devices was examined by in-line coupling of SLM extractions to CE for direct analysis of four model basic drugs in dried blood spot extracts. Excellent repeatability of the hyphenated technique was achieved (RSD ≤ 7.6%), transfer of analytes across the SLM ranged from 23 to 73% and limits of detection were as low as 0.07 μg/mL.

  • Czech name

  • Czech description

Classification

  • Type

    D - Article in proceedings

  • CEP classification

  • OECD FORD branch

    10406 - Analytical chemistry

Result continuities

  • Project

    <a href="/en/project/GA18-13135S" target="_blank" >GA18-13135S: Application of capillary electrophoresis in dried blood spots analysis</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Article name in the collection

    CECE 2018. 15th International Interdisciplinary Meeting on Bioanalysis

  • ISBN

    978-80-904959-5-1

  • ISSN

  • e-ISSN

  • Number of pages

    4

  • Pages from-to

    257-260

  • Publisher name

    Ústav analytické chemie AV ČR, v. v. i.

  • Place of publication

    Brno

  • Event location

    Brno

  • Event date

    Oct 15, 2018

  • Type of event by nationality

    WRD - Celosvětová akce

  • UT code for WoS article