Capillary electrophoresis as a sample separation step to mass spectrometry analysis: A primer

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F23%3A00572002" target="_blank" >RIV/68081715:_____/23:00572002 - isvavai.cz</a>
Result on the web
<a href="https://hdl.handle.net/11104/0342843" target="_blank" >https://hdl.handle.net/11104/0342843</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.trac.2023.117093" target="_blank" >10.1016/j.trac.2023.117093</a>

Result language
angličtina
Original language name
Capillary electrophoresis as a sample separation step to mass spectrometry analysis: A primer
Original language description
Capillary electrophoresis (CE) is a separation technique that offers high resolution, great sensitivity, and short processing times. Mass spectrometry (MS) accurately characterizes ionized species based on mass and fragmentation patterns that identify analytes by their mass to charge ratio. Powerful analytical systems are enabled by hyphenating CE with MS. Introducing a sample separated into individual zones minimizes ion suppression and significantly enhances the capacities of MS. This review article is intended as an introduction to scientists and professionals who are already familiar with electrophoresis and are interested in learning about the analytical potential of CE-MS systems. Working principles and basic instrumentation, including the CE-MS interfaces, are included as the robust and sensitive interfaces are crucial to the acceptance of CE-MS systems in the (bio)analytical practice. A discussion of recent reports on CE-MS systems provides an overview of the latest advances, and the conclusions speculate on future developments.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2023
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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