Determination of Pathogens by Electrophoretic and Spectrometric Techniques
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081715%3A_____%2F24%3A00573363" target="_blank" >RIV/68081715:_____/24:00573363 - isvavai.cz</a>
Result on the web
<a href="https://hdl.handle.net/11104/0343826" target="_blank" >https://hdl.handle.net/11104/0343826</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10408347.2023.2219748" target="_blank" >10.1080/10408347.2023.2219748</a>
Alternative languages
Result language
angličtina
Original language name
Determination of Pathogens by Electrophoretic and Spectrometric Techniques
Original language description
In modern medical diagnostics, where analytical chemistry plays a key role, fast and accurate identification of pathogens is becoming increasingly important. Infectious diseases pose a growing threat to public health due to population growth, international air travel, bacterial resistance to antibiotics, and other factors. For instance, the detection of SARS-CoV-2 in patient samples is a key tool to monitor the spread of the disease. While there are several techniques for identifying pathogens by their genetic code, most of these methods are too expensive or slow to effectively analyze clinical and environmental samples that may contain hundreds or even thousands of different microbes. Standard approaches (e.g., culture media and biochemical assays) are known to be very time- and labor-intensive. The purpose of this review paper is to highlight the problems associated with the analysis and identification of pathogens that cause many serious infections. Special attention was paid to the description of mechanisms and the explanation of the phenomena and processes occurring on the surface of pathogens as biocolloids (charge distribution). This review also highlights the importance of electromigration techniques and demonstrates their potential for pathogen pre-separation and fractionation and demonstrates the use of spectrometric methods, such as MALDI-TOF MS, for their detection and identification.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
<a href="/en/project/NU22-05-00110" target="_blank" >NU22-05-00110: Poly-microbial basis of non-healing wounds infections and therapeutic potential of 3D bioprinting-based concept for infections treatment</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Critical Reviews in Analytical Chemistry
ISSN
1040-8347
e-ISSN
1547-6510
Volume of the periodical
54
Issue of the periodical within the volume
8
Country of publishing house
US - UNITED STATES
Number of pages
24
Pages from-to
2960-2983
UT code for WoS article
001009236200001
EID of the result in the Scopus database
2-s2.0-85162063929