Effect of Ni ion release on the cells in contact with NiTi alloys

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081723%3A_____%2F20%3A00534086" target="_blank" >RIV/68081723:_____/20:00534086 - isvavai.cz</a>

Alternative codes found

RIV/00216224:14110/20:00114179

Result on the web

<a href="https://link.springer.com/article/10.1007/s11356-019-07506-8" target="_blank" >https://link.springer.com/article/10.1007/s11356-019-07506-8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11356-019-07506-8" target="_blank" >10.1007/s11356-019-07506-8</a>

Result language

angličtina

Original language name

Effect of Ni ion release on the cells in contact with NiTi alloys

Original language description

Nickel-titanium alloys have been used in medical applications for several years, however, biocompatibility of the materialnremains controversial. In the present study, the human umbilical vein endothelial cells (HUVEC) were cultured in contact withnthe nitinol used in two different heat treatment surface modifications—helium and hydrogen. The amount of Ni ions releasednfrom these alloys in contact with HUVEC was measured in media and in the cells by ICP-MS. An increased release of Ni ionsnwas detected in He alloy compared with H2 alloy modification with an elevation with the metal exposition duration (24 h vs.n72 h). The cells contained the Ni ions in both selected alloy modifications with the lower levels in H2 alloys. To evaluate thenpotential of multiple metal applications, similar values were observed in media and in cell suspension for all surface modificationncombinations. The model analysis of effect of metal ion release on distant cells in the body showed that the concentration isninterestingly similar to concentrations in cells in direct contact with the metal alloy. The cells are able to regulate the concentrationnof Ni ions within the cell. According to our best knowledge, the study for the first time describes the presence of Ni ions releasednfrom nitinol directly in the cells. In the case of the H2 modification, the lowest levels of Ni ions were detected both in medium andnin the cells, which likely increases the biocompatibility of the nitinol alloy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

20802 - Bioremediation, diagnostic biotechnologies (DNA chips and biosensing devices) in environmental management

Project

<a href="/en/project/GA15-16336S" target="_blank" >GA15-16336S: Interstitial impurities in NiTi-based shape memory alloys</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Environmental Science and Pollution Research

ISSN

0944-1344

e-ISSN

—

Volume of the periodical

27

Issue of the periodical within the volume

8

Country of publishing house

DE - GERMANY

Number of pages

9

Pages from-to

7934-7942

UT code for WoS article

000517084600014

EID of the result in the Scopus database

2-s2.0-85077201115