The brain changes of anisotropy in MAM model of schizophrenia in rat

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F13%3A00421027" target="_blank" >RIV/68081731:_____/13:00421027 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The brain changes of anisotropy in MAM model of schizophrenia in rat

Original language description

Methylazoxymethanol acetate(MAM)-exposed rats were used to parallel neuropathological abnormalities seen in schizophrenia patients. Corpus callosum (cc), the largest white matter structure in the brain, and anterior commissure (aca) were measured by diffusion tensor imaging(DTI) to verify decreased fractional anisotropy (FA) in white matter tracts connecting frontal and temporal or parietal lobes, suggested to reflect disturbedstructural connectivity and demyelination in schizophrenia [2]. Our aim was to confirm this model by DTI of white matter structures so the MAM-exposed rats could be used for testing new antipsychotic drugs.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

BH - Optics, masers and lasers

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Magma

ISBN

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ISSN

1352-8661

e-ISSN

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Number of pages

1

Pages from-to

294

Publisher name

Springer-Verlag

Place of publication

Berlin

Event location

Tolouse

Event date

Oct 3, 2013

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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