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Quantitative Contrast-Enhaced Ultrasound Comparsion Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F13%3A00421683" target="_blank" >RIV/68081731:_____/13:00421683 - isvavai.cz</a>

  • Result on the web

    <a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2013.01.020" target="_blank" >http://dx.doi.org/10.1016/j.ultrasmedbio.2013.01.020</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2013.01.020" target="_blank" >10.1016/j.ultrasmedbio.2013.01.020</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Quantitative Contrast-Enhaced Ultrasound Comparsion Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease

  • Original language description

    The aim of this study was to determine whether there are differences in absolute blood flow between patients with Crohn's disease with inflammation or fibrosis using contrast-enhanced ultrasound. Eighteen patients with fibrotic disease and 19 patients with inflammation were examined. Video sequences of contrast data were analyzed using a pharmacokinetic model to extract the arterial input and tissue residue functions with a custom software, enabling calculation of the absolute values for mean transit time, blood volume and flow. Feasibility of the examination was 89%. The fibrosis group had lower blood volume (0.9 vs. 3.4 mL per 100 mL tissue; p = 0.001) and flow (22.6 vs. 45.3 mL/min per 100 mL tissue; p = 0.003) compared with the inflammation group.There was no significant difference in mean transit time (3.9 vs. 5.5 s). In conclusion, absolute perfusion measurement in the gastrointestinal wall using contrast-enhanced ultrasound is feasible. There seems to be reduced blood volume an

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FS - Medical facilities, apparatus and equipment

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GAP102%2F12%2F2380" target="_blank" >GAP102/12/2380: Perfusion Analysis Using MRI and Ultrasound</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2013

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Ultrasound in Medicine and Biology

  • ISSN

    0301-5629

  • e-ISSN

  • Volume of the periodical

    39

  • Issue of the periodical within the volume

    7

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    10

  • Pages from-to

    1197-1206

  • UT code for WoS article

    000320587900008

  • EID of the result in the Scopus database