Quantitative Contrast-Enhaced Ultrasound Comparsion Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F13%3A00421683" target="_blank" >RIV/68081731:_____/13:00421683 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2013.01.020" target="_blank" >http://dx.doi.org/10.1016/j.ultrasmedbio.2013.01.020</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ultrasmedbio.2013.01.020" target="_blank" >10.1016/j.ultrasmedbio.2013.01.020</a>
Alternative languages
Result language
angličtina
Original language name
Quantitative Contrast-Enhaced Ultrasound Comparsion Between Inflammatory and Fibrotic Lesions in Patients with Crohn's Disease
Original language description
The aim of this study was to determine whether there are differences in absolute blood flow between patients with Crohn's disease with inflammation or fibrosis using contrast-enhanced ultrasound. Eighteen patients with fibrotic disease and 19 patients with inflammation were examined. Video sequences of contrast data were analyzed using a pharmacokinetic model to extract the arterial input and tissue residue functions with a custom software, enabling calculation of the absolute values for mean transit time, blood volume and flow. Feasibility of the examination was 89%. The fibrosis group had lower blood volume (0.9 vs. 3.4 mL per 100 mL tissue; p = 0.001) and flow (22.6 vs. 45.3 mL/min per 100 mL tissue; p = 0.003) compared with the inflammation group.There was no significant difference in mean transit time (3.9 vs. 5.5 s). In conclusion, absolute perfusion measurement in the gastrointestinal wall using contrast-enhanced ultrasound is feasible. There seems to be reduced blood volume an
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FS - Medical facilities, apparatus and equipment
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GAP102%2F12%2F2380" target="_blank" >GAP102/12/2380: Perfusion Analysis Using MRI and Ultrasound</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Ultrasound in Medicine and Biology
ISSN
0301-5629
e-ISSN
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Volume of the periodical
39
Issue of the periodical within the volume
7
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
1197-1206
UT code for WoS article
000320587900008
EID of the result in the Scopus database
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