Using Single-Channel Blind Deconvolution to Choose the Most Realistic Pharmacokinetic Model in Dynamic Contrast-Enhanced MR Imaging
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F15%3A00451248" target="_blank" >RIV/68081731:_____/15:00451248 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s00723-015-0679-y" target="_blank" >http://dx.doi.org/10.1007/s00723-015-0679-y</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00723-015-0679-y" target="_blank" >10.1007/s00723-015-0679-y</a>
Alternative languages
Result language
angličtina
Original language name
Using Single-Channel Blind Deconvolution to Choose the Most Realistic Pharmacokinetic Model in Dynamic Contrast-Enhanced MR Imaging
Original language description
In dynamic contrast-enhanced magnetic resonance imaging, there has been no consensus in the choice of the pharmacokinetic model. In this paper, a new approach for assessment of the most realistic model for a given tissue is presented. Non-blind and single-channel blind deconvolution algorithms were used in quantitative magnetic resonance dynamic contrast-enhanced imaging of the mouse masseter muscle to compare the realism of two different pharmacokinetic models for the tissue residue function. The firstwas the adiabatic approximation tissue homogeneity model (aaJW) and the second, the two-compartment exchange model (2CXM). Normals and mice treated with the substance C48/80 were studied. C48/80 increases both blood flow and contrast leakage in muscle substantially. The obtained approximation accuracy was evaluated for both pharmacokinetic models. In addition, the arterial input functions (aifs) estimated using blind deconvolution were compared to the corresponding observed aifs. The hy
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
BH - Optics, masers and lasers
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Magnetic Resonance
ISSN
0937-9347
e-ISSN
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Volume of the periodical
46
Issue of the periodical within the volume
6
Country of publishing house
DE - GERMANY
Number of pages
17
Pages from-to
643-659
UT code for WoS article
000354620900004
EID of the result in the Scopus database
2-s2.0-84937762704