Hemodynamic modelling in the calf — A pilot study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F16%3A00474796" target="_blank" >RIV/68081731:_____/16:00474796 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.22489/CinC.2016.149-433" target="_blank" >http://dx.doi.org/10.22489/CinC.2016.149-433</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.22489/CinC.2016.149-433" target="_blank" >10.22489/CinC.2016.149-433</a>

Result language

angličtina

Original language name

Hemodynamic modelling in the calf — A pilot study

Original language description

With increasing age, the cardiovascular system loses its efficiency. The goal of this work was to investigate the hemodynamic system response to a head-up tilt test in two groups of different aged people. We used a model for describing this response in the right calf based on a non-invasive, non-occlusive, bioimpedance signal measurement technique. A decrease in the bioimpedance value in the calf during the head-up tilt test is associated with the accumulation of blood in the calf, which can be expressed by a model parameter. Subjects were examined in both a head-up tilt test and a supine position. 50 healthy non-smoking volunteers were divided into two groups according to age. The impedance signal during the tilt test for each subject was fitted by a model exponential function: Z0 model EF(t) =A exp(-t/B)+C, where Z0 model EF(t) is the calculated model of electrical impedance in the calf by an exponential function, A is the amplitude of impedance change, B is the time constant of the impedance decrease, C is the value of the steady state after the tilt test and t denotes time. A lower time constant B shows a faster filling of the vascular system in the investigated part. The Mann-Whitney test (p-value<,0.005) revealed that the time constant B for the older group was significantly lower than for the young group (145.24+/- 80.28 vs. 239.23+/-136.59 sec.). A lower time constant value means a faster response to blood filling in the lower limbs and directly reflects decreased vessel elasticity. This time constant was lower in the older group. The results show increased vessel stiffness in old age and could lead to a non-invasive evaluating the cardiovascular system state.

Czech name

—

Czech description

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Type

D - Article in proceedings

CEP classification

—

OECD FORD branch

20601 - Medical engineering

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Computing in Cardiology (CinC) 2016

ISBN

978-1-5090-0896-4

ISSN

2325-8861

e-ISSN

—

Number of pages

4

Pages from-to

525-528

Publisher name

Computing in Cardiology

Place of publication

Vencouver

Event location

Vencouver

Event date

Sep 11, 2016

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

000405710400132