Interictal invasive very high-frequency oscillations in resting awake state and sleep

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F23%3A00579364" target="_blank" >RIV/68081731:_____/23:00579364 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/23:00079747 RIV/00216224:14110/23:00133460 RIV/00216305:26220/23:PU152449

Result on the web

<a href="https://www.nature.com/articles/s41598-023-46024-z" target="_blank" >https://www.nature.com/articles/s41598-023-46024-z</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1038/s41598-023-46024-z" target="_blank" >10.1038/s41598-023-46024-z</a>

Result language

angličtina

Original language name

Interictal invasive very high-frequency oscillations in resting awake state and sleep

Original language description

Interictal very high-frequency oscillations (VHFOs, 500-2000Hz) in a resting awake state seem to be, according to a precedent study of our team, a more specific predictor of a good outcome of the epilepsy surgery compared to traditional interictal high-frequency oscillations (HFOs, 80-500Hz). In this study, we retested this hypothesis on a larger cohort of patients. In addition, we also collected patients' sleep data and hypothesized that the occurrence of VHFOs in sleep will be greater than in resting state. We recorded interictal invasive electroencephalographic (iEEG) oscillations in 104 patients with drug-resistant epilepsy in a resting state and in 35 patients during sleep. 21 patients in the rest study and 11 patients in the sleep study met the inclusion criteria (interictal HFOs and VHFOs present in iEEG recordings, a surgical intervention and a postoperative follow-up of at least 1year) for further evaluation of iEEG data. In the rest study, patients with good postoperative outcomes had significantly higher ratio of resected contacts with VHFOs compared to HFOs. In sleep, VHFOs were more abundant than in rest and the percentage of resected contacts in patients with good and poor outcomes did not considerably differ in any type of oscillations. In conclusion, (1) our results confirm, in a larger patient cohort, our previous work about VHFOs being a specific predictor of the area which needs to be resected, and (2) that more frequent sleep VHFOs do not further improve the results.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Scientific Reports

ISSN

2045-2322

e-ISSN

2045-2322

Volume of the periodical

13

Issue of the periodical within the volume

1

Country of publishing house

US - UNITED STATES

Number of pages

11

Pages from-to

19225

UT code for WoS article

001108929300063

EID of the result in the Scopus database

2-s2.0-85175805492