Spectral and network investigation reveals distinct power and connectivity patterns between phasic and tonic REM sleep

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081731%3A_____%2F25%3A00643252" target="_blank" >RIV/68081731:_____/25:00643252 - isvavai.cz</a>

Alternative codes found

RIV/00159816:_____/25:00082348

Result on the web

<a href="https://academic.oup.com/sleep/article/48/8/zsaf133/8139669" target="_blank" >https://academic.oup.com/sleep/article/48/8/zsaf133/8139669</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/sleep/zsaf133" target="_blank" >10.1093/sleep/zsaf133</a>

Result language

angličtina

Original language name

Spectral and network investigation reveals distinct power and connectivity patterns between phasic and tonic REM sleep

Original language description

Although rapid eye movement (REM) sleep is often thought of as a singular state, it consists of two substates, phasic and tonic REM, defined by the presence (respectively absence) of bursts of rapid eye movements. These two substates have distinct EEG signatures and functional properties. However, whether they exhibit regional specificities remains unknown. Using intracranial EEG recordings from 31 patients, we analyzed expert-labeled segments from tonic and phasic REM and contrasted them with wakefulness segments. We assessed the spectral and connectivity content of these segments using Welch's method to estimate power spectral density and the phase locking value to assess functional connectivity. Overall, we found a widespread power gradient between low and high frequencies (p < 0.05, Cohen's d = 0.17 +/- 0.20), with tonic REM being dominated by lower frequencies (p < 0.01, d = 0.18 +/- 0.08), and phasic REM by higher frequencies (p < 0.01, d = 0.18 +/- 0.19). However, some regions, such as the occipito-temporal areas as well as medial frontal regions, exhibit opposite trends. Connectivity was overall higher in all bands except in the low and high ripple frequency bands in most networks during tonic REM (p < 0.01, d = 0.08 +/- 0.09) compared to phasic REM. Yet, functional connections involving the visual network were always stronger during phasic REM when compared to tonic REM. These findings highlight the spatiotemporal heterogeneity of REM sleep which is consistent with the concept of focal sleep in humans.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30210 - Clinical neurology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Sleep

ISSN

0161-8105

e-ISSN

1550-9109

Volume of the periodical

48

Issue of the periodical within the volume

8

Country of publishing house

US - UNITED STATES

Number of pages

15

Pages from-to

zsaf133

UT code for WoS article

001517678500001

EID of the result in the Scopus database

2-s2.0-105013317854