Wild cyclic voles maintain high neutral and MHC diversity without strong evidence for parasite-mediated selection
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F14%3A00432240" target="_blank" >RIV/68081766:_____/14:00432240 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10682-014-9709-8" target="_blank" >http://dx.doi.org/10.1007/s10682-014-9709-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10682-014-9709-8" target="_blank" >10.1007/s10682-014-9709-8</a>
Alternative languages
Result language
angličtina
Original language name
Wild cyclic voles maintain high neutral and MHC diversity without strong evidence for parasite-mediated selection
Original language description
The major histocompatibility complex (MHC) is an important component of vertebrate immune defense involved with self/nonself recognition and disease susceptibility. The high variability of genes of the MHC is thought to arise from both parasite-mediatedand sexual selection. An outstanding question involves the degree to which balancing selection can oppose genetic drift to maintain high MHC diversity in the face of population bottlenecks. To address this question we examined genetic diversity and population structure at neutral (microsatellite) and MHC genes in montane voles [Microtus montanus (Peale, 1848)] subject to high amplitude population fluctuations, and compared these to measures of infection by common gastrointestinal parasites. We found high neutral and MHC allelic variability, indicating low impacts of genetic drift despite large fluctuations in population size. Greater MHC diversity did not predict lower parasite richness or infection by the two most common endoparasites
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EG - Zoology
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Evolutionary Ecology
ISSN
0269-7653
e-ISSN
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Volume of the periodical
28
Issue of the periodical within the volume
5
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
19
Pages from-to
957-975
UT code for WoS article
000340496000010
EID of the result in the Scopus database
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