Comparative genomic analysis of co-occurring hybrid zones of house mouse parasites Pneumocystis murina and Syphacia obvelata using genome polarisation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68081766%3A_____%2F25%3A00640470" target="_blank" >RIV/68081766:_____/25:00640470 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/25:00142575
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.70044" target="_blank" >https://onlinelibrary.wiley.com/doi/epdf/10.1111/mec.70044</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1111/mec.70044" target="_blank" >10.1111/mec.70044</a>
Alternative languages
Result language
angličtina
Original language name
Comparative genomic analysis of co-occurring hybrid zones of house mouse parasites Pneumocystis murina and Syphacia obvelata using genome polarisation
Original language description
Parasites are expected to hybridise in similar ways to free-living organisms, although this may be modified by their reduced genome architecture. Recombinant strains and taxa of hybrid origin can be studied in nature where hosts come into secondary contact. Here we apply genome-wide analysis to parasites from a contact previously characterised for many individuals using classical markers. The host contact is the European house mouse hybrid zone, the parasites are lung fungus Pneumocystis and gut pinworm Syphacia. The genomic (many loci) and classical (many-individual) results are broadly consistent in scale and centring of transitions across the host hybrid zone. Whole mitogenome comparisons confirm earlier suggestions that parasite divergence is low compared to their hosts, perhaps due to reduced-genome stabilising selection. In the recombining genome, we are able to show blocks of the parasite genome of alternating host origin, including one Pneumocystis strain which appears to be an F3+ cross and one recombinant Syphacia strain found over multiple localities. Functional analyses of introgressing genes show enrichment for genes likely important for parasitic lifestyle. Our work confirms that evolutionary models of hybridisation apply equally to hosts and their parasites.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30303 - Infectious Diseases
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Molecular Ecology
ISSN
0962-1083
e-ISSN
1365-294X
Volume of the periodical
34
Issue of the periodical within the volume
21
Country of publishing house
US - UNITED STATES
Number of pages
23
Pages from-to
e70044
UT code for WoS article
001592304500001
EID of the result in the Scopus database
2-s2.0-105018761153