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Kinetics of formation of specific styrene oxide adducts in double-stranded DNA.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F01%3A19010056" target="_blank" >RIV/68378041:_____/01:19010056 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023795:_____/01:00004789

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Kinetics of formation of specific styrene oxide adducts in double-stranded DNA.

  • Original language description

    In order to compare the intrinsic reactivity of the different nucleophilic sites in DNA towards SO and to evaluate the candidates for human biomonitoring we have determined the second-order tate constants and stabilities of several SC-adducts in double-stranded DNA. These include ?- and -isomers of N7-substituted and ?N2-substituted guanines, ?- and N3-substituted and ?N6-substituted adenines as well as N3-and ?N4-substituted cytosines.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EA - Morphology and cytology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA313%2F99%2F1460" target="_blank" >GA313/99/1460: Mechanisms of genotoxic effects and prospects to the evaluation of individual susceptibility to styrene exposure</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2001

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Chemico-Biological Interactions

  • ISSN

    0009-2797

  • e-ISSN

  • Volume of the periodical

    138

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    IE - IRELAND

  • Number of pages

    13

  • Pages from-to

    111-124

  • UT code for WoS article

  • EID of the result in the Scopus database