Mice with astrocyte-directed inactivation of connexin43 exhibit increased exploratory behaviour, impaired motor capacities, and changes in brain acetylcholine levels.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F03%3A19033134" target="_blank" >RIV/68378041:_____/03:19033134 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Mice with astrocyte-directed inactivation of connexin43 exhibit increased exploratory behaviour, impaired motor capacities, and changes in brain acetylcholine levels.
Original language description
We investigated the effects of the astrocyte-directed inactivation of Cx43 (gap junctions forming connexin protein) on mouse behaviour and brain neurochemistry. Transgenic animals showed increased exploration in the open field and steeper learning coursein water maze, they showed increased acetylcholine content in the frontal cortex.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FH - Neurology, neuro-surgery, nuero-sciences
OECD FORD branch
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Result continuities
Project
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Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Journal of Neuroscience
ISSN
0953-816X
e-ISSN
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Volume of the periodical
18
Issue of the periodical within the volume
N/A
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
2313-2318
UT code for WoS article
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EID of the result in the Scopus database
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