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DNA repair and cyclin D1 polymorphisms and styrene-induced genotoxicity and immunotoxicity

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F05%3A00026191" target="_blank" >RIV/68378041:_____/05:00026191 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    DNA repair and cyclin D1 polymorphisms and styrene-induced genotoxicity and immunotoxicity

  • Original language description

    Styrene is a chemical widely in the plastic industry. The main pathway of styrene metabolism in human occurs via the oxidation to styrene-7,8-oxide (7,8-SO). The aim of this study was the investigation of a minor metabolic route, involving the oxidationof the arene moiety of styrene, by means of the characterization of the conjugated urinary metabolites of 4-vinylphenol (4-VP).

  • Czech name

    Polymorfizmy DNA reparačních genů a cyklínu D1 ve vztahu ke genotoxicitě a imunotoxicitě styrénu

  • Czech description

    Styrén má široké použití v průmyslu plastických hmot. Hlavní metabolická cesta probíhá přes oxidaci na styrén 7,8 oxid (7,8 SO). Cílem této studie bylo vyšetřit minoritní metabolickou dráhu, která zahrnuje oxidaci na aromatickém kruhu styrénu, charakterizací konjugovaných metabolitů 4 ? vinylfenolu (4VP).

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FM - Hygiene

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA310%2F03%2F0437" target="_blank" >GA310/03/0437: New aspects in understanding styrene genotoxicity: the role of DNA repair,new reactive metabolites and secondary oxidative stress</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Toxicology and Applied Pharmacology

  • ISSN

    0041-008X

  • e-ISSN

  • Volume of the periodical

    207

  • Issue of the periodical within the volume

    -

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    "S302"-"S309"

  • UT code for WoS article

  • EID of the result in the Scopus database