Biomarkers of exposure to tobacco smoke and environmental pollutants in mothers and its transplacental transfer to the foetus. Part II: Oxidative damage

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F09%3A00330450" target="_blank" >RIV/68378041:_____/09:00330450 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Biomarkers of exposure to tobacco smoke and environmental pollutants in mothers and its transplacental transfer to the foetus. Part II: Oxidative damage

Original language description

Oxidative damage to DNA, lipids and proteins was measured in 80 newborns and 79 mothers. There was no difference in oxidation of either marker in newborns born to mothers exposed and unexposed to tobacco smoke. Protein oxidation was comparable in the umbilical cord and in maternal blood plasma. Lipid peroxidation was higher in newborns than in mothers. Protein oxidation and lipid peroxidation in cord blood correlated with those in maternal plasma. DNA oxidation in newborns was correlated was bulky DNA adducts in lymphocyte DNA of newborns and mothers. The results underlined close correlation of oxidative stress markers between newborns and mothers and a relationship between oxidative stress and induction of DNA adducts.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

DN - Environmental impact on health

OECD FORD branch

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Project

<a href="/en/project/2B06088" target="_blank" >2B06088: Application of toxicogenomics to study mechanisms of the action of environmental pollutants on human health.</a><br>

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2009

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Mutation Research

ISSN

0027-5107

e-ISSN

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Volume of the periodical

669

Issue of the periodical within the volume

1-2

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

7

Pages from-to

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UT code for WoS article

000271065800004

EID of the result in the Scopus database

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