Astrocytes in Alzheimer's Disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F10%3A00349472" target="_blank" >RIV/68378041:_____/10:00349472 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Astrocytes in Alzheimer's Disease

Original language description

In this manuscript we covered the specific involvement of astrocytes in various neurodegenerative diseases including Alzheimer's disease, Amyotrophic lateral sclerosis, Parkinson's disease and various forms of dementia. We demonstrate that early stages of neurodegenerative processes are associated with atrophy of astroglia, which causes disruptions in synaptic connectivity, disbalance in neurotransmitter homeostasis and neuronal death through increased excitotoxicity. Which at the later stages astrocytes became activated and contribute to neuro-inflammatory component of neurodegeneration.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FH - Neurology, neuro-surgery, nuero-sciences

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neurotherapeutics

ISSN

1933-7213

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

4

Country of publishing house

US - UNITED STATES

Number of pages

14

Pages from-to

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UT code for WoS article

000282198500007

EID of the result in the Scopus database

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