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Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F10%3A00350688" target="_blank" >RIV/68378041:_____/10:00350688 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Time-resolved FRET between GPCR ligands reveals oligomers in native tissues

  • Original language description

    The artical "Time-resolved FRET between GPCR ligands reveals oligomers in native tissues" shows for the first time that G-protein coupled receptors (GPCRs) form oligomeric complexes also in native tissues and not only in heterologous expression systems.Oligomerization of these receptors regulates their function and pharmacological properties and thus influences all the processes controled by GPCRs that are involved in the cell response to extracellular stimuli.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2010

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Nature Chemical Biology

  • ISSN

    1552-4450

  • e-ISSN

  • Volume of the periodical

    6

  • Issue of the periodical within the volume

    8

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

    000280096600009

  • EID of the result in the Scopus database