Control of the extracellular ionic environment and volume

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F13%3A00388979" target="_blank" >RIV/68378041:_____/13:00388979 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1093/med/9780199794591.003.0034" target="_blank" >http://dx.doi.org/10.1093/med/9780199794591.003.0034</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/med/9780199794591.003.0034" target="_blank" >10.1093/med/9780199794591.003.0034</a>

Result language
angličtina
Original language name
Control of the extracellular ionic environment and volume
Original language description
It is evident that glial cells play an important role in different brain functions. Voltage- and ligand-activated channels and a number of transport mechanisms on the glial membrane allow for the maintenance of ionic and volume homeostasis, which in turnaffect neuronal function. The production of extracellular matrix molecules by activated astrocytes further hinders already impaired diffusion and contributes to an increase in tortuosity. Astrocytes can thus be viewed as active elements in signal transmission as they affect both synaptic as well as extrasynaptic volume transmission.
Czech name
—
Czech description
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Project
<a href="/en/project/GA309%2F09%2F1597" target="_blank" >GA309/09/1597: Role of the extracelullar matrix in the extracelullar space diffusion parameter changes during aging and the metabolic syndrome</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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