Oxidative stress in newborns by different modes of delivery

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F16%3A00480253" target="_blank" >RIV/68378041:_____/16:00480253 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12110/16:43899428

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Oxidative stress in newborns by different modes of delivery

Original language description

OBJECTIVES: The aim of our study is to investigate the impact of the type of delivery -vaginal vs. cesarean section on oxidative damage determined as the lipid peroxidation (15-F2t-isoprostane (15-F2t-IsoP) in the cord blood of newborns and venous blood from mothers in two localities with different levels of air pollution: Ceske Budejovice (CB), a locality with a clean air, and Karvina, a locality with high air pollution.nRESUTLS: In Karvina, the concentration of PM2.5 was higher than in CB in the summer 2013 (mean +/- SD: 20.41 +/- 6.28 vs. 9.45 +/- 3.62 mu g/m3, p< 0.001) and in the winter 2014 (mean +/- SD: 53.67 +/- 19.76 vs. 27.96 +/- 12.34 mu g/m3, p< 0.001). Similarly, the concentration of B[a] P was higher in Karvina than in CB in the summer 2013 (mean +/- SD: 1.16 +/- 0.91 vs. 0.16 +/- 0.26 ng/m3, p< 0.001) and in the winter 2014 (5.36 +/- 3.64 vs. 1.45 +/- 1.19 ng/m3, p< 0.001). Delivery procedures differed by the type of anesthesia, at the Cesarean section in CB was used general anesthesia in 73.8% vs. 20.8% in Karvina (p< 0.001), epidural anesthesia in CB in 26.2% vs. 77.1% in Karvina (p< 0.001), at vaginal delivery was local anesthesia used in CB in 58.9% vs. 14.1% in Karvina (p< 0.001). In CB was oxidative stress higher after vaginal delivery (101.7 +/- 31.0 pg 15-F2t-isoP/ml plasma) vs. Cesarean section (83.9 +/- 26.9 pg 15-F2t-isoP/ml plasma, p< 0.001), no difference between the type of delivery was observed in Karvina. nCONCLUSION: No difference between the types of delivery was observed in mothers in CB as well as in Karvina. Oxidative stress in newborns in Karvina was significantly affected by the concentrations of PM2.5 and B[a] P in the polluted air.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30304 - Public and environmental health

Project

<a href="/en/project/GA13-13458S" target="_blank" >GA13-13458S: Impact of air pollution to genome of newborns</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Neuroendocrinology Letters

ISSN

0172-780X

e-ISSN

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Volume of the periodical

37

Issue of the periodical within the volume

6

Country of publishing house

SE - SWEDEN

Number of pages

12

Pages from-to

445-451

UT code for WoS article

000398579900007

EID of the result in the Scopus database

2-s2.0-85018675893