The use of pulsed magnetic fields to increase the uptake of iron oxide nanoparticles by living cells
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F17%3A00487767" target="_blank" >RIV/68378041:_____/17:00487767 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/17:00484345 RIV/00023001:_____/17:00076218
Result on the web
<a href="http://dx.doi.org/10.1063/1.5007797" target="_blank" >http://dx.doi.org/10.1063/1.5007797</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1063/1.5007797" target="_blank" >10.1063/1.5007797</a>
Alternative languages
Result language
angličtina
Original language name
The use of pulsed magnetic fields to increase the uptake of iron oxide nanoparticles by living cells
Original language description
Remote control of the interaction of magnetic nanoparticles with cells is fundamental to any potential downstream applications of magnetic nanoparticles such as gene and drug delivery vehicles and magnetic cell labeling. Thus, approaches based on the application of external magnetic fields to increase the efficiency of magnetic cell labeling are desirable. Here, we report a simple approach that enhances magnetic cell labeling using pulsed magnetic fields. The rate of uptake of superparamagnetic iron oxide nanoparticles (SPIONs) and transport across the cell membrane were enhanced upon application of a high intensity (7T) short pulse width (similar to 15 mu s) magnetic field. We present a quantitative analysis and mechanistic explanation of how a pulsed magnetic field influences the uptake of SPIONs by cells. Our findings offer insights into the mechanics of how pulsed magnetic fields can be effectively used to optimize magnetic cell labeling, which can provide a basis for better controlled biomedical applications of SPIONs. Published by AIP Publishing.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10610 - Biophysics
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Physics Letters
ISSN
0003-6951
e-ISSN
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Volume of the periodical
111
Issue of the periodical within the volume
24
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
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UT code for WoS article
000418098900051
EID of the result in the Scopus database
2-s2.0-85038445881