Utilization of Micronucleus Assay in Nanotoxicology Research-Current State of the Art

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F18%3A00499218" target="_blank" >RIV/68378041:_____/18:00499218 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Utilization of Micronucleus Assay in Nanotoxicology Research-Current State of the Art
Original language description
Micronucleus assay, which has been used for almost sixty years, is one of the basic methodological approaches of genetic toxicology. This is also evident from more than 10,500 references found using the keyword “micronucleus” in PubMed database. These studies, both in vitro and in vivo, which are discussed in the context of deleteriousness for humans, concern the evaluation of cytotoxicity and genotoxicity of numerous chemicals and in the last decade also nanomaterials (NMs) and nanoparticles (NPs). The aim of this mini-review was to track down the story of the development, improvement and possibilities of the micronucleus assay and revise its significant achievements in the field of nanotoxicology research in both in vitro and in vivo studies.
Czech name
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Czech description
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Project
<a href="/en/project/LO1508" target="_blank" >LO1508: Genomics and proteomics in the study of mechanisms of biological effects of produced nanoparticles</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name
Nanostructures in Biomedicine: Their Regenerative and toxic properties
ISBN
978-80-906655-7-6
Number of pages of the result
5
Pages from-to
16-20
Number of pages of the book
198
Publisher name
Proxima Tisk, s.r.o.
Place of publication
Praha 3
UT code for WoS chapter
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