Glia and Neural Stem and Progenitor Cells of the Healthy and Ischemic Brain: The Workplace for the Wnt Signaling Pathway
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F20%3A00538317" target="_blank" >RIV/68378041:_____/20:00538317 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11130/20:10412836 RIV/68378050:_____/20:00538317
Result on the web
<a href="https://www.mdpi.com/2073-4425/11/7/804" target="_blank" >https://www.mdpi.com/2073-4425/11/7/804</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/genes11070804" target="_blank" >10.3390/genes11070804</a>
Alternative languages
Result language
angličtina
Original language name
Glia and Neural Stem and Progenitor Cells of the Healthy and Ischemic Brain: The Workplace for the Wnt Signaling Pathway
Original language description
Wnt signaling plays an important role in the self-renewal, fate-commitment and survival of the neural stem/progenitor cells (NS/PCs) of the adult central nervous system (CNS). Ischemic stroke impairs the proper functioning of the CNS and, therefore, active Wnt signaling may prevent, ameliorate, or even reverse the negative effects of ischemic brain injury. In this review, we provide the current knowledge of Wnt signaling in the adult CNS, its status in diverse cell types, and the Wnt pathway's impact on the properties of NS/PCs and glial cells in the context of ischemic injury. Finally, we summarize promising strategies that might be considered for stroke therapy, and we outline possible future directions of the field.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30103 - Neurosciences (including psychophysiology)
Result continuities
Project
—
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Genes
ISSN
2073-4425
e-ISSN
2073-4425
Volume of the periodical
11
Issue of the periodical within the volume
7
Country of publishing house
CH - SWITZERLAND
Number of pages
25
Pages from-to
804
UT code for WoS article
000557220400001
EID of the result in the Scopus database
2-s2.0-85088413914