A rare case of non-traumatic spinal epidural hematoma in lumbar region associated with apixaban therapy

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68378041%3A_____%2F21%3A00552910" target="_blank" >RIV/68378041:_____/21:00552910 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11150/21:10435160 RIV/00179906:_____/21:10435160

Result on the web

<a href="https://link.springer.com/article/10.1007/s11239-021-02462-y" target="_blank" >https://link.springer.com/article/10.1007/s11239-021-02462-y</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1007/s11239-021-02462-y" target="_blank" >10.1007/s11239-021-02462-y</a>

Result language

angličtina

Original language name

A rare case of non-traumatic spinal epidural hematoma in lumbar region associated with apixaban therapy

Original language description

Spontaneous spinal epidural hematoma (SSEH) is a very rare clinical entity with potential diagnostic difficulties and which can result in severe neurological deficit. The etiology of this rare condition is largely not known, but with potential predisposition in patients on anticoagulation medication. This includes the novel anticoagulants with direct inhibition of the factor Xa mechanism (DOACs). These medications are supposed to have more predictable pharmacokinetics with fewer severe haemorrhagic adverse events in comparison with standard warfarin therapy. However, in the last few years, an increasing number of case reports have been published of haemorrhage into the central nervous system. We present a case of non-traumatic spinal epidural hematoma in the lumbar region in a patient on chronic apixaban therapy. To the best of our knowledge, it is the first described SSEH in the lumbar region associated with apixaban therapy.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30103 - Neurosciences (including psychophysiology)

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Thrombosis and Thrombolysis

ISSN

0929-5305

e-ISSN

1573-742X

Volume of the periodical

52

Issue of the periodical within the volume

4

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

1215-1219

UT code for WoS article

000648020700001

EID of the result in the Scopus database

2-s2.0-85105358929